Genetic Disease Screening Kit

Sickle Cell Anaemia is a common genetic disease that causes long rods in red blood cells, giving them a "sickled" appearance. These cells get stuck in small capillaries of the blood stream leading to oxygen deprivation that causes pain and organ damage. Sickle Cell Anaemia is caused by a single point mutation in the haemoglobin gene that results in a faulty protein. In this experiment, your students will investigate the restriction enzyme that discriminates between HbA (normal) and HbS (disease) genes and perform a simulated test on a patient.
Kit includes:
• Instructions & Ready-to-Load™ DNA samples for 24 gels.
All you need:
• Electrophoresis apparatus, power supply, agarose powder, buffer solution, automatic micropipette and tips, balance, microwave or hot plate, visualization system.
Storage:
• Room temperature stable. Storage of DNA samples in the freezer is recommended.